Good morning again @sakota. I also have COPD but I had to look up alpha 1 carrier. I have never been tested. How did you come to know that your COPD is genetic? Many of us here have multiple diseases. I'm 72 and started my journey when I was 51. Just off the cuff of my brain I think that you may have to ask a geneticist about any connection of any other illnesses and your genetic factor. I found this for you: https://www.alpha1.org/what-is-alpha1 This goes into a lot of detail How has your COPD been treated? I have 3 inhalers. Do you presently have an active cancer?