Hello, @pankaj - I'm sorry to hear you've experienced these ups and downs with your anxiety and depression and your meds. Good that you have a doctor who is sensitive to making adjustments for you along the way. I'd like to invite @lillee @jfanesi @eburning @cdcc @yolandaf into this conversation to offer any insights from their experiences with pregabalin (Lyrica) on whether the dosage is likely to stabilize at some level in the future, or if it will likely lose it's effectiveness with time. @healthytoday and @becsbuddy may also have some thoughts on this.

@smilie - I agree with @grandmar - I'm terribly sorry you're suffering right now. You'd mentioned you have medicine and are getting professional help, and that you have an emergency crisis unit to call. You also talked about considering going to the hospital. I'd strongly suggest that you 1) call your medical professional, 2) call your emergency crisis unit, or 3) at least call one of your adult children, if you are continuing to think of the "S" word. We care and want you to be safe and helped through this difficult time.