@hosta Yes, I had a series 3 medial branch blocks in the neck area, and 5 -7 in the lumbar area. Each time I thought the first one was working, so they did the second one. But they really didn't work for me. I personally know one may that they made a big difference for him. I was given a IV and when I got in the procedure room, the anesthesia was injected in the IV. It was just enough to put me in NA NA land. The Doctor does use a x-ray to guide the needle where he has decided where the problem is coming from. Out of all that I had, I only had trouble with the last one and I am sorry to say that one really did hurt. So it does work on some people and most of the time there is no problem. It is just like any other procedure. Good Luck. God Bless!