Hi, @ssaygi - I'd like to add my welcome to Mayo Clinic Connect. I've given this discussion you've started placement in both our Epilepsy & Seizures group as well as our About Kids & Teens group, so that it might get responses from a variety of members.

I'd like you to meet members like @patrassi @rachelanne @crstyday40 @lethargic @lmcquade, who have talked about epilepsy or seizure disorders. They may have some thoughts on your 5-year-old grandsons' epilepsy risk with your daughter having had that diagnosis, and perhaps some of them have looked into questions on the heritability of this disease.

@ssaygi - do you know what the boys' doctor has said about their risk of this disease?