Hi, Sorry to hear about all those problems. My wife has had a lot of those symptoms and yet her blood tests came back negative. Finally at John's Hopkins in Baltimore they diagnosed her with MTHFR, She has a double gene mutation which makes her allergic to all foods enriched with folic acid. Most breads are enriched. Most pasta are enriched. Some white rice is enriched. This is methyleneterahydrofolate reductase or MTHFR. Elevated levels of homocystines in the blood. Her normal blood levels were fine but the cells were not getting the B vitamins since they were blocked from getting from the blood to the cells by the MTHFR. You can google MTHFR for more information. This is a gene blood test instead of a regular blood test in order to determine if you have that. There are two kinds of MTHFR. It is inherited and both her parents had it but showed no signs but she got both genes so was worse. Her parents also grew their own food and nothing was enriched in those days. Again, her present diet is fresh vegetables, meat and potatoes. A lot of people can minimize symptoms by going on a gluten free diet since glutens are enriched. Gene Position C677T. She is reading off some of her medical records. A1298C is the other gene. Once she stopped eating enriched foods her brain fog, chronic pain, tiredness, etc. High homocystine levels are often an indicator. 23 & Me gene testing kit can test for it if the doctor won't test for it but a doctor needs to read the results. She takes a folate for that and NOT a folic acid supplement. Folic acid=enriched which is bad. Hope that is another avenue for you to investigate.