When I was medicated for a severe MAC infection, I had 60 days of IV Amikasin , moxyfloxicillin and was also taking Ethambutol daily and Clairithromycin BID. I was automatically ordered to have my eye exams every three months or sooner if I felt I noticed a change. When I had been taking it for about eleven months , I did have some blurring in my rt eye. I had an MRI and the Optic nerve showed some inflammation. I immediately quit taking that med. I remained in the Moxifloxicllin and Clairithromycin orally for the complete one and a half years. My rt ear hearing is not as good as the left. I had no choice but the meds and I am doing really well ever since. I was very sick for three years before a bronchoscopy and C&S was finally done . Sometimes you do what you have to do to stay alive.