← Return to Immunotherapy: Keytruda (pembrolizumab)

Discussion
ina3 (@ina3)

Immunotherapy: Keytruda (pembrolizumab)

Lung Cancer | Last Active: Mar 21, 2021 | Replies (58)

Comment receiving replies
@edb

Hello everyone,

Wishing you and your loved ones peace, and healing.

My wife was diagnosed with stage 4 lung cancer in January 2019. Not wanting to wait potentially weeks on her genetic testing results, her oncologist opted to start her right away on Keytruda & two chemotherapies (alimta & ?). She did very well through 13 treatments, experiencing steady regression to what could technically be termed partial remission with little or no side effects. She’s started her own successful part-time career coaching business and we’re very grateful!

The last 3 treatments saw her deal with increasing sluggishness in her digestive process post-treatment, to the point of recently dealing with moderate abdominal pain within minutes of eating & increasing constipation. It got bad enough where we finally experimented with a 24-hour clear liquid/jello fast, which seem to help to reset her digestive system without drugs. She’s pain-free currently and back on a regular diet.

Around this same time she had a CT scan based on her digestive issues which showed steady state in her previously affected cancerous areas, but an increase in size in several lymph nodes in her abdominal region – a new development. Her oncologist has decided to stop immunotherapy/chemotherapy for now, monitor the new lymph node activity via scan, get a biopsy of the lymph nodes if needed, and potentially switch to genetic treatment if necessary (she tested 67% positive for ROS1 expression).

Which is a looonng way to my question: what are your experiences with swollen lymph nodes related to immunotherapy? Obviously we’re hoping this is her body simply saying “enough treatment for now” and not an unwanted new twist in the plot. But I haven’t been able to find much info on patient experiences with swollen lymph nodes related directly to immunotherapy in general, or Keytruda in particular.

Thankful for whatever you share,

Ed

Jump to this post


Replies to "Hello everyone, Wishing you and your loved ones peace, and healing. My wife was diagnosed with..."

I’m one month behind your wife and was on same chemo and immune treatment. The last three treatments (21 days per treatment) I’ve had the same digestive problems. I’m also on OxyContin 24-7 so I’ve been watching to make sure things keep moving. Must say I have cramps bad one day and within 5-7 hours I have blow outs than ok. Go back 27Th of January for blood work and Scan to see what’s happening.right lung tumor 4 stage cancer, nodules in kidney, stomach and cells in left lung. Was interesting to her my problems are not unusal. Thank you!🙏🏻

Hi, @edb – glad you connected with @richcolleen. I wanted to let you know I've moved your post here to an existing thread, "Immunotherapy and chemo; Keytruda side effects," so that you can connect with others here also talking about this topic.

Please meet @ina3 @schmeeckle64 @hopeful33250 @2onlow8 @doughy42 and others.

You indicated you'd know more in late Jan/early Feb. Do you have another appointment with the oncologist at that time? Genetic testing results?

  Request Appointment