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How did you manage the pain side effects of Prolia?
Osteoporosis & Bone Health | Last Active: Feb 18, 2023 | Replies (259)Comment receiving replies
@sue225 I became very sick for about ten days and initially thought I had a bacterial infection related to my bronchiectasis. Muscle and joint pain followed, persisting for a few months. I had previously been on Prolia and had taken a year holiday to give my body a rest from the medications (and returned to osteoporosis levels). So, I saw a new endocrinologist at Mayo (my previous provider had retired locally) and we had decided to return to Prolia as it had worked well for me. Then, fast forward six months and I fell down some stairs and broke my foot (which involved a long recovery process). The doctor switched my medication to Tymlos for bone building and I initially tolerated it but slowly I began suffering ever increasing leg pain. So, now it’s back to Prolia. I am not considering discontinuing it as I have been on and off these medications and I have not been able to maintain healthy bone density without them. I hope this helps.
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@migizii thanks for sharing your experience with Reclast. I have had good results according to the dexa scan which I had after a year and a half of being on Prolia. Very good results. You need to know one very important thing about Prolia. If you stop Prolia after having had about three injections (one is okay), you risk getting vertebral compression fractures up to two years after stopping if you do not start another osteoporosis medication. This is referred to as a "relay" drug. Amgen tells you this in their information pamphlet to both patients and doctors and doctors sometimes neglect mentioning this little detail. Drug holidays from Prolia are no longer recommended.
In my particular situation it's a bit like (if you'll forgive the expression) "damned if you do, and damned if you don't. (Maybe). To date, I have not had fractures.
Very sorry to hear about your foot and the long recovery process. I wish you good health. It's a leap of faith with these meds.