Hi @goldengirl2 and others, Chiming in with my experience. I'm five years and a few months out from dx of UPSC. Had surgery w/ Da Vinci robot and a superb, skilled, kind surgeon here in Virginia, followed by a 'sandwich regime': three rounds chemo Taxol/ Carboplatin, 25 sessions of external radiation and 3 sessions of brachytherapy internal rad, 3 final sessions of chemo. At one point in 2013 it was suggested by a consulting oncologist that external radiation might not be necessary in addition to all the rest, but my surgeon recommended I hit it with everything and so I did. I'm completely NED and we celebrated the five-year mark this spring (my family). Some of the side effects I think are by this time considered permanent: neuropathy (chemo-induced in feet) and digestive changes (rad-induced). It was a pretty scary experience certainly, my tumor was 90% through uterine wall but no lymph node involvement. The standard of care changes a bit over time and I try to keep up somewhat with the literature (am too new here to post links, it's not allowed for me, but there are some good recent ones found easily on google by inputting UPSC and looking in the last year) but by no means qualified to weigh in medically. Just a survivor's experience. Best of luck to you. If I can answer any questions please just ask.