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Positive ANA and ENA Panel

Autoimmune Diseases | Last Active: Jan 2, 2022 | Replies (12)
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@annedodrill44

I recently had blood work and my ANA portion came back 1:1280 homogenous. Normal range is 1:80 or less. Mayo is ordering additional testing and an autoimmune panel. Has anyone else experienced an elevated ANA? If so, what did you learn? I am a 74 year old woman in otherwise excellent health, and am told there are many positive ANA readings in older women. Thank you for any enlightenment!

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Replies to "I recently had blood work and my ANA portion came back 1:1280 homogenous. Normal range is..."
Colleen Young, Connect Director | @colleenyoung | Sep 26, 2019

Hi annedodrill44, I moved your message to this existing discussion about ANA testing in the Autoimmune Diseases group (https://connect.mayoclinic.org/group/autoimmune-diseases/). I did this so you can meet other members talking about elevated ANA levels, like @slim1938 @carpe_bean @bluebird6156 @jenniferhunter @lioness @becsbuddy and others.

You might also be interested in this discussion on Connect:
- What can cause ANA titre of 1:2560? https://connect.mayoclinic.org/discussion/what-can-cause-ana-titre-of-12560/

The antinuclear antibodies (ANA) test detects autoantibodies in the blood that may indicate an autoimmune disorder. You can read more about the test and why it is done here: https://labtestsonline.org/tests/antinuclear-antibody-ana

Anne, what additional tests are being ordered for you? What condition, if any, is being suspected?

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moselurl | @moselurl | Oct 17, 2019

I have, once a out 30 years ago, and again about 5 years ago, diagnose with CREST Scleroderma, 30 years ago it was erythemia

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