@jeaniebean Pharmaceuticals are tricky. Since going on an AI in January 2018, I lost about 25 lbs. in two years without dieting or increasing exercise... then my weight leveled off during the pandemic SIP business when exercise time plummeted with the close of my gym. I was not unhappy with the weight loss, but it alarmed my oncologist at first. At my age, it likely has more to do with loss of muscle mass than fat loss... but nonetheless, you never know how your body will react to an AI until you go on one.