Here's what I did, and it worked, no problems. I asked my Psychiatrist M.D. if I could, after many years on Cymbalta, change to Lexapro, as I felt that I had "burned out" on Cymbalta, i.e., it was no longer working very well. She agreed to let me switch, I've read good things about Lexapro, and what she did was to - I was taking 60mg a day of Cymbalta, the M.D. Psychiatrist gave me a 5-day supply of 30 mg. Cymbalta, down from the 60 mg, and simultaneously started me on the Lexapro starting dosage of 10mg, and I had, gratefully, no problem transitioning off the Cymbalta and onto the Lexapro, BUT, I want to add that 1) I did this under an expert doctor's supervision and 2) I take other medications that may have made transitioning off the Cymbalta and onto the Lexapro in 5 days that may have made the transition easier and painless, namely, I also take 1.25 mg clonazepam (I hate clonazepam and would never ever advise someone to take a benzo as THAT withdrawal is horrible!! (I went - under a doctor's careful supervision!!!! from 4 mg. daily to now 1.25 mg and soon will be off, again, under my doctor's careful supervision) off clonazepam/Klonopin and I take Buspirone (I like that medication better but want to get off it asap, too, as I'm finding that walking 30 mins. every day and other exercises like yoga stretching takes away my anxiety disorder largely and "positive thinking." Thinking only positive thoughts and avoiding stressful-to-me thoughts and people (reducing social media!!!) and giving myself permission to pursue as hobbies activities I love and volunteer work which is amazing.