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Stem cell treatment for peripheral neuropathy - any good?

Neuropathy | Last Active: Aug 31, 2020 | Replies (25)
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@nightgig

I attended a meeting/consultation with the Dr. (Chiropractor) yesterday and was told that I could get the feet free of tingling or the hands, for $5000. The feet procedure is more common and thus, more reliable. The stem cell treatment for the hands was estimated as for 40 - 60% and the fett were 80-90% effective. I like the Dr. and he did not in any way seem either incompetent or a salesman for the procedures. I told him that I would get advice from my MD.

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John, Volunteer Mentor | @johnbishop | Sep 28, 2018

@nightgig it's good you are doing research to help you make an informed decision. It would be interesting to hear what your doctor thinks. There is a lot of hope out there for those of us with PN for stem cell therapy. My own personal opinion is that they have not really shown that it works yet for nerve regeneration because they haven't had any FDA approved clinical trials to show any kind of success. Also, at the last meeting of the Minnesota Neuropathy Association we had a speaker William Hoffman of the U of M Medical School who has been involved in documenting and writing about stem cell research for many years. My notes from the meeting about his outlook for treating peripheral neuropathy:

Outlook for Treating Peripheral Neuropathy
-- Stem cell transplantation remains largely at the pre-clinic stage
-- Proper stem cell homing and migration remain a concern
-- Stem cell transplantation has shown some benefit but is still inferior to nerve repair with conventional techniques
-- Pre-clinical and eventually clinical studies comparing different types of stem cell are needed
-- Optimal Schwann cell differentiation has yet to be achieved

A little explanation for the last bullet:
The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration
— https://www.cell.com/neuron/abstract/S0896-6273(17)30843-7
The repair Schwann cell and its function in regenerating nerves
— https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929314/

If you do decide to go with the stem cell treatment, I would really like to hear how it went for you.

Good luck with whatever you decide.

John

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