They have lessened quite a bit. And being overly emotional has gone away. I am still on the big 3 orally and will add nebulized amilacin this week. Also the amounts of the big 3 will be adjusted so that I am getting just what I need according to my blood levels. This is such an individual thing and it is wise to not only monitor these drugs but adjust the amounts given according to our reactions to them. Good luck!