Laura34. I have been taking the Amikacin/ Arikayce since last October. I have been taking it every other day with literally no side effects. At the daily dose I began to loose my voice so my pulmonologist changed me to every other day. I am not on the big 3 because 2 of those drugs affect my heart rate adversely and my doc felt I was not able to tolerate them. I was scheduled for a ct in June but doc has said we will wait until August because of the corona virus. At last ct scan I have nodules and 3 cavitation lesions