Hi, @tiffanyb - welcome to Mayo Clinic Connect. With your son's ups and downs with the Kleine Levin syndrome, I can imagine it's been heartbreaking.

I'd like to introduce you to some other members who've participated in this discussion, like @momnxtdr @pbledso24 @jenniferhunter @kaseykalb @hopeful33250 and others, who may have some thoughts for you as you've not seen any recovery for your son in the last 2 weeks since his extreme fatigue and severe sense of derealization. Though @ihatediabetes' son has a different diagnosis, she may also have some perspective for you, and @Jody3 @barsta also may have some input.

Will you share more about the derealization you've noted in your son?