Hi @pcspetpro. Glad @kanaazpereira invited me into this discussion again. I share your confusion about whether statins are reliable responses to calcification of arteries or not. I'm particularly interested in "Statins Promote Coronary Calcification? Study Says Yes . . ." It looks to me as though this is a common case of a bad misleading headline.

In the first paragraph of the story under the headline, you'll see that "In the analysis, statins, specifically high-intensity statin therapy, actually promoted coronary calcification despite regressing the volume of coronary atheroma." Notice that the headline gives no attention or credence to "high-intensity statin therapy" as a major factor in calcium contents of debris deposits on the internal lining of an artery. As you suggest, there was some mysterious capability of statins to affect changes in calcium and low-density lipids and doing so in contrasting directions under differing conditions. Unfortunately, the mystery was reported for this study four years ago and might have been solved more recently, but if so, I didn't find that information. Even so, give that report a good read and see if you get a different impression of how calcium deposits in arteries are affected by statins. As Kanaaz says, that's a matter of long-term controversy.