My wife is 9 months post surgery and using Creon, cholestyramine, and immodium and still has persistent diarrhea. Her fecal tests and scans have been negative for mets and structural issues. Recent discussion with the gastro's nurse practitioner are leading to another test, SIBO for bacterial overgrowth. Even though the fecal bacterial tests have all been negative, they don't reveal possible bacteria in the small intestine. While the test itself is non-invasive, it does require pre-fasting and due to travel and the test taking as much as 4-5 hours, she'll miss multiple meals. The oncologist has suggested skipping the test and going straight to the antibiotics that would be prescribed if the SIBO test was positive. I'm leaning to the test, my wife is leaning to just go for the prescription although with great reservations.

Has anyone who experienced the ongoing diarrhea taken the SIBO/antibiotics route and did it help?