@carnet I have to agree with @jackiem95, that is a very high dose. I went to a doctor who is a specialist in Barrett's Esophagus when I first had mine and he gave me two omeprazole a day, each 20 mg. He said my PCP would probably be alarmed at such a high dose but he wanted me to start on that for two or three months, I forget exactly how long because it was quite a while ago, and then I was reduced to once a day.

That gastroenterologist was the best in my opinion. He unfortunately moved from Mass General to Columbia Presybitarian in NYC. I am seriously considering going to NYC for my next appointment. My daughter lives there so I could stay with her.
JK