Just wondering, @iksuffolk, if you are wanting to go off of omeprazole because of bone loss? There are other OTC products that help such as Pepcid and it is not a PPI as is omeprazole.

You do not mention your age and if you are post-menopausal but all of those are important factors.

Have you had a check of your parathyroid hormones? The parathyroid is different that the thyroid although it is located near the thyroid. Hypoparathyroidism can cause bone loss as well. If that has not been checked (by a simple blood test) you might consider requesting that when you talk with your doctor next time. Here is some information on hypoparathyroidism from Mayo Clinic's website. It discusses how hypoparathyroidism can affect the bones as well as other parts of the body.
https://www.mayoclinic.org/diseases-conditions/hypoparathyroidism/symptoms-causes/syc-20355375
Will you post again the let me know how you are doing?