Connect
← Return to Long term Polymyalgia Rheumatica
Discussion
Long term Polymyalgia Rheumatica
Polymyalgia Rheumatica (PMR) | Last Active: Aug 5, 2021 | Replies (13)Comment receiving replies
Thank you for your reply, John. I appreciate the Pub Med article on methotrexate use with prednisone. The addition of methotrexate to my med “cocktail” was to, of course, get off prednisone. In fact, I am now taking 2 mg. more than when I started methotrexate. I guess another question is whether
people with a lengthier case of PMR have seen doctors at the Mayo Clinic (or other prestigious clinic) for a second opinion...and what was their experience.
Replies to "Thank you for your reply, John. I appreciate the Pub Med article on methotrexate use with..."
Sorry I haven't posted for a while but I do want to let you know that I am now down to 5 mg prednisone since I first started in March 2017 at 15 mg, and for the past two months have also been on methothextrate (6 mgs per week, down from 8 which did not agree with me). I am doing reasonably OK but find the metho makes me tired more easily - I see my doctor soon so will see what she thinks. I am determined not to have to increase the prednisone so suffer from stiffness in the first part of the mornings but lots of exercise seems to stave it off for the rest of the day. Night time sleeping is still a problem but Tylenol Arthritis helps me through.
Hope this info is of help and I will update again soon.
Sandra
Thank you for the update Sandra @paulinef. I also suffer from joint and muscle stiffness and have found that if I do about 15 to 30 minutes of mild exercise in the morning when I first get up it helps the rest of the day also. I have a relatively inexpensive recumbent exercise bike / elliptical combination exercise machine and was doing mostly the bike but recently switched to using the elliptical to add more weight bearing exercise to build up my leg strength.
Is the night time sleeping problem due to pain from the PMR? Some people have had success changing the time they take their or splitting the dosage between morning and evening. You might want to discuss it with your doctor to see what they say. If the methotrexate makes you tired maybe you could take it at bedtime?
John
Sorry I should have said I am on six x 2.5 mg Methotrexate per week
Connect
Hi @flicka, I'm not sure if it helps you but another tool I use to find research type information is Google Scholar (https://scholar.google.com/). It has date links on the side so that you can select the newest articles and show patents and citations along with the search results. I did a search using the terms - methotrexate use with prednisone for PMR. Here are the results:
-- https://scholar.google.com/scholar?hl=en&as_sdt=0%2C24&q=methotrexate+use+with+prednisone+for+PMR&btnG=
My first round with PMR took 3 years to get off of prednisone and the rheumatologist that diagnosed my PMR at Rochester Mayo Clinic had shared with me the story of one of his patients who was going back and forth between 1 mg and 1/2 mg dosage for a couple of years before he was able to get off with no pain. I don't know how long he had been diagnosed with PMR but I'm pretty sure if was longer than the 3 years I was struggling with at the time.
John