@lmh7 I had the symptoms with Rifabutin and changed to Rifampin. I did good during the first 3 months but have more stomach aching and full feeling now with some weight loss and of course I can fall asleep really fast at night. I am on my 7th month and hoping to make it as long as I can. Some days are OK and others are not OK. I has labs and liver tests were OK except the GGT which most MD's don't order was a little elevated. They want me to continue and recheck in 3 months. Hopefully I can keep up the dosing. Has anyone had any changes in liver function labs while on the meds?