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Small Fiber Neuropathy

Neuropathy | Last Active: Nov 22 5:50am | Replies (106)

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@wolfbauer

I have apparently had non-length dependent SFN for a while, along with a myriad of other conditions including a spinal syrinx between T5 and T9, and three messed up discs from a car accident (C4-C5, L4-L5, L5-S1). I also have a schwannoma on the T8 thoracic nerve which is shielded by my rib and inoperable (radiation is currently the only treatment option being offered to me). I finally had the punch biopsy and was formally diagnosed with it this past summer. It's progressed to autonomic nervous system dysfunction at this point; I have gastroparesis, severe nausea and weight loss (50 pounds in 5 weeks), random tachycardia while resting or sleeping (I've woken up with a heart rate of 110), syncope without prodromal symptoms (that was a gem to find out I can now pass out at any time with no warning), and within the past two months, have begun having what I call 'hot flashes' (I'm a 31-year-old male) alternating with chills, but I DO NOT have a fever during those occasions. My neurologist told me that it was very common in SFN, but that he has yet to learn of any treatment to prevent/treat it. I have terrible insomnia where I can end up sleep anywhere from 1 day to 4 days, so when I do actually get sleep, it's important to me and obviously frustrating to wake up because I feel like I'm in a sauna, ten minutes later freezing, then another ten minutes later on fire again. Has anyone experienced this, and if they have, have you found a treatment for it? I was curious if anyone has tried clonidine (can be used for hot sweats/flashes and excessive sweating).

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Replies to "I have apparently had non-length dependent SFN for a while, along with a myriad of other..."

@wolfbauer there is another discussion on Connect where members have mentioned clonidine in their posts.

Groups > Heart & Blood Health > New to the world of Hypertension Meds
-- https://connect.mayoclinic.org/discussion/new-to-the-world-of-hypertension-meds/

I'm tagging @predictable to see if he may have any information or suggestions for you. Also, Mayo Clinic has some information here that may be helpful:

Clonidine (Oral Route)
-- https://www.mayoclinic.org/drugs-supplements/clonidine-oral-route/description/drg-20063252