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Depression & Anxiety | Last Active: Mar 6, 2023 | Replies (200)

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@gailb

I read this in the NORML Newsletter today and thought some here may benefit from the information. Gail, Volunteer Mentor

Patients Replace Opioids With Cannabis
Thursday, 07 June 2018

Chronic Pain Patients Replace Opioids With Cannabis
Cleveland, OH: More than two-thirds of chronic pain patients registered to legally access medical cannabis products substitute marijuana for prescription opioids, according to data published in The Journal of Headache and Pain.

Investigators from the United States and Canada assessed the use of medical cannabis and prescription drugs in a cohort of over 2,000 Canadian patients licensed to access marijuana products. Among those patients with a primary diagnosis of chronic pain, 73 percent reported substituting cannabis in place of opioids. Among those patients diagnosed specifically with headache/migraine, cannabis was frequently reported as a substitute for other medications - including opiates (43 percent), anti-depressants (39 percent), NSAIDS (21 percent), triptans (8 percent), and anti-convulsants (8 percent).

"Most patients in the pain groups reported replacing prescription medications with medicinal cannabis, the most common of which were opiates/opioids across all patient groups," authors concluded. "This is notable given the well-described 'opioid-sparing effect' of cannabinoids and growing abundance of literature suggesting that cannabis may help in weaning from these medications and perhaps providing a means of combating the opioid epidemic."

For more information, contact Paul Armentano, NORML Deputy Director, at: paul@norml.org. Full text of the study, "Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort," appears in The Journal of Headache and Pain. NORML's fact-sheet highlighting the relevant, peer-reviewed research specific to the relationship between cannabis and opioids is available online.

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Replies to "I read this in the NORML Newsletter today and thought some here may benefit from the..."

@gailb, Thanks for posting this. Since I was prescribed Marinol(sp?), a synthetic form of cannabis, for appetite enhancement after a major surgery due to not eating enough to promote healing, I knew this to be a fact. My appetite certainly did improve, but the period of time when I could get refills and had the marinol, were the only completely pain free weeks I have had since 2006.
Gary