Good morning @lioness There are no official guidelines- I think for now it's a crap shoot because it's unregulated. However, due to a lot of the postings here, you can see some of the answers. This is my experience: At my compassion center I was told to start with a full dropper from a 100 ml bottle. That was 10 mgs of CBD oil along with flavoring. If that didn't work to increase it. Taken daily and at the same time it will build up in your system. Here is some help
https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-treatment-with-medical-cannabis/
https://www.dawsoncreekmirror.ca/opinion/columnists/knowing-the-difference-between-hemp-oil-and-cbd-oil-1.23381063
https://www.medicalnewstoday.com/articles/317221.php
Hope this helps