I was diagnosed with BE in 2008 and started taking omeperozole 20 mg once a day. I worried about taking so long but in June 2016, it went to low dysplasia and he increased My dosage to 40 mg a day. Then in February it went to high dysplasia and he started doing an ablation every three months and asked that I take 40 mg twice a day. That was a lot it seemed because I worry about the long term effects too. I must take it however because in iJune, I went to MDAnderson and had an EMR and he found a trace of the adenocarcinoma cell so I go in every three months now for an ablation and when we are rid of BE we can probably go for the endoscopy less often. I am wondering what it looks like now Due to go back in June 6.and hope I have some good news. I am told I will have to have these every three months for the rest of my life. I appreciate hearing from others about their treatment and outcome.