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PMR and Methotrexate

Polymyalgia Rheumatica (PMR) | Last Active: 2 days ago | Replies (199)

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@amom7

Anyone still following? Have been on methotrexate 3-4months. Had relapsed on prednisone dose of 12.5. Now reduced to 7.5. With folic acid, side effects of methotrexate are minimal. Still painful muscles, especially in am, but tolerable. So helpful to hear from others dealing with pmr.

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Replies to "Anyone still following? Have been on methotrexate 3-4months. Had relapsed on prednisone dose of 12.5. Now..."

Hello @amom7, welcome to Mayo Clinic Connect. You are definitely not alone. There are a lot of us still following the discussion. Thankfully my PMR is in remission. I've had 2 occurrences of PMR, both were treated with 20 mg prednisone until I was able to taper off - 3 years for the first occurrence and 1-1/2 years for the second occurrence. I think we all learn to live with a little pain while we try to taper off. Does your doctor or rheumatologist have any suggestions for tapering off? I've never been treated with methotrexate so have no experience with it. What dosage of methotrexate are you taking with the prednisone?

Hello, hopefully my small contribution might help. I was taking 10 mgs of methotrexate once a week with folic acid for over seven years. I stopped abruptly and there were no side affects. Peach