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PMR and Methotrexate

Polymyalgia Rheumatica (PMR) | Last Active: Apr 12 4:04pm | Replies (172)

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@paulinef

An update on methotrexate: been on it for about a month along with 4 mg prednisone until first I came down with a respiratory bug caught off my husband. It took ages to shake off but I had no reason to think I should come off the metro until I cut my calf quite badly on a sharp object. This evolved into a nasty infection and I had to go on heavy duty antibiotics - I wasn’t warned that Metho hinders healing so continued taking it until I finally thought to call the rheumatologist who said to come off it until the cut had healed and no longer on Cephalexin.. So the warning to people on metho is to be very careful not to catch anything or cut yourself and if so, do not continue to stay on it. Neither the pharmacist or the two Doctors had warned me to come off it when it was prescribed unfortunately. ....

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Replies to "An update on methotrexate: been on it for about a month along with 4 mg prednisone..."

Interesting!!!
I have been weaning Prednisone, was down to 4mg with return of joint pain so Rheum increased Prednisone to 9mg. I had an office visit the following week and he encouraged starting on Methotraxate 10mg q week which I did saying it was to help wean off Prednisone.
10 days later I developed a respiratory infection with fever which was dx as pneumonia! I felt bad! But better now after ABX
I should note that I’m 71 but until PMR 1 1/2 yr ago I had no health issues, was physically active, hiking/camping etc. Cant even remember that last time I even had a cold..
I have read the study that John noted above…..while small, it was encouraging(?) so Im going to stay with MTX and see how it goes. I’m SO ready to be off prednisone!!!