An update on methotrexate: been on it for about a month along with 4 mg prednisone until first I came down with a respiratory bug caught off my husband. It took ages to shake off but I had no reason to think I should come off the metro until I cut my calf quite badly on a sharp object. This evolved into a nasty infection and I had to go on heavy duty antibiotics - I wasn’t warned that Metho hinders healing so continued taking it until I finally thought to call the rheumatologist who said to come off it until the cut had healed and no longer on Cephalexin.. So the warning to people on metho is to be very careful not to catch anything or cut yourself and if so, do not continue to stay on it. Neither the pharmacist or the two Doctors had warned me to come off it when it was prescribed unfortunately. ....