I have Bronchiectasis since 2009 and have had Pseudomonus for several years now. I have been treated with IV antibiotics but it just comes back eventually. I am now resistant to Cipro and Astreonam and others. I was then treated with Toby (Tobramycin) in the nebulizer but it was hard to tolerate for me. Most seem to be able to use it though. Now I use nebulizer Amikacin but I can only tolerate it once a day. I am off for 28 days and then back on for 28 more days. So far so good. I have whitish or clear sputum but still a lot of coughing and some wheezing as I also have asthma.