@src3acs I suppose just because I don't have the problem with shortness of breath, it doesn't mean other people who have been diagnosed with MAC don't share your experience. Let's hope others in this group can provide more information on that front. When I was first diagnosed with MAC, I was also given the option of going on the drug treatment or not. After considering the pros and cons of the drug effects on the infection as well as on my body (other organs), I decided to wait and see. My pulmonologist agreed with me. Since the initial diagnosis, I have had chest X-rays and a CT scan. The results point to improvement. As a result my doctor thinks we should continue the wait-and-see path. There are so many people in this group who have the same diagnosis as you and me. Let's hope that there are others who also share your symptoms and are able to provide you with more reassuring answers to your questions.