Hello Mama- I agree with you that Mayo Connect shows that there is hope- there always is hope and it's horrible when we feel like there isn't any. All medicines have side effects and I also agree that they can change a person't chemical makeup-does it ever go back to normal? I don't know. Chemical intervention is a blunt instrument. They can be very dangerous so we know that we have to stand up for ourselves and really research and question our doctors. You are a success story Mama-an an inspiration to us all.