Dear Merry, Volunteer Mentor, I have been on Cymbalta for years, for depression as well as fibromyalgia. I will share with you that I was having breakthrough depression, night terrors, and dreams that were too horrendous to mention. My good doctor put me on Wellbutrin and a low dose of Xanex, for anxiety. I am doing very well, thriving even. Chronic, debilitating pain changes a person. I have lost friends over this. But now I have a new purpose here on Mayo Clinic Connect. A community where we can share our stories and be encouraged. To feel that there is hope, and that one is not alone. I was given amphetamines by my doctor when I was only 11 or 12 years old. The doctor put me on a strict diet that was very low calorie. I feel in my heart that those pills did a number on my brain circuitry. I was too young to be given such strong medication. All medications have side effects. Guess I will never know for sure the effect those pills had on me. But that is the past. I look forward to what the future will bring. Health and healing for us all is my prayer! Mamacita