I have been administering CBD 20:1 tincture for my 31 yr old son who has autism and a great deal of anxiety for the past 5 months So far it has helped him a great deal; according to his staff and observations I have made . I weaned him off 2 drugs prescribed by his psychiatrist Guanficine and clonipin. in the past 5 months. I an now trying to wean him off an atypical antipsychotic. I am tapering very slowly/ I did not like the idea of polypharmacy ( he was on 5 medications) to control anxiety and aggression, irritability . Generally he has seemed much happier, calmer, more focused in the past 5 months which did not happen when he was on the 5 "prescribed" medications. I recently consulted with a nurse practitioner who specializes in medical cannabis to assist me with dosing, type of CBD and weaning him off psych meds if possible. I am taking data on his moods, indicators of stress , behaviors etc to assist me and his physician to determine if when we can lower the dose of the pharmaceuticals. . Finding the right brand and dose can be difficult . Nurse practitioner told me it is better to look at the amt of milligrams of CBD in the oil vs just the ratio. He takes the tincture sblingually under the tongue although it can certainly be added to food. It can take anywhere from about 30 minutes to an hour to see the difference in his mood , generally calmer, less irritable and perseverative . I understand if you want a faster acting effect you can vape it but I have not tried that with him. Hope this is helpful.