I had pmdd all my life and 2 years ago I had surgery for that and am at 46 years on surgical menopause with mood and sleep disturbance I use zoloft and an estradiol patch but still some liability and fatigue because I also have an autoinmune condition. Both are chronic conditions so that contribute to the mood liability and anxiety. I am 5 month stable and high productivity with adding cbd oul. For me the only one that works is hempworx cbd oil. I started on 5 drops and after 3 days 1 drop more (6 drops) 3 days more and 7 drops so on till 10 drops that I started to feel that my brain fog left I felt focus centered and without fatigue and no anxiety. I am now 5 months taking 20 drops am and 20 drops pm with much success. I take care pretty much about my sleep so add a tiny dose of seroquel and that's enough. Don't use benzodiazepines and hace no anxiety nor mood liability and a healthy deep sleep. I need to have routines and no excesses at all even if it's about working out and doing good thinks. Everything has to be moderate and flow a nutritional plan. Hope this helps