Speaking from experience. I have been using CBD oil 300 mg to control major- depression cycles for some time, and so far is working. I started using CBD since I was off Psych-medication for some time now. I was skeptic in using something coming of Marijuana because of the bad rap it has on society; fortunately the good chemical cbd don't give you a high or any psychotic ride since it doesn't have it's evil brother TCH. My wife is being using it for pain management after back surgery that she was on morphine for years, and the pain scale have gone from a 6 to a 2-3. +++ Make sure you buy quality oil that contain around 60% CBD as the main ingredient with vitamins B; no matter which form you decide to use at a reputable seller since there's many counterfeit being sold as genuine out there in the internet !+++ psst an added bonus: the product works well for our insomnia !!! 😀