Hello @hollywoodal, I would also like to welcome you to Mayo Connect. You have mentioned taking 12.5 mg twice a day, but I'm not sure what medication you are referring to. Can you explain more? It sounds like it is helpful to you in that you notice a feeling better after a couple of hours of taking the med. I would be interested in knowing more about this drug.

I can understand your problems with Metoprolol. My response to that was tough, to say the least. My cardiologist switched me to Atenolol, much better!