Well here it is 4 months later after I first posted asking if it's possible to get reinfected while being on the Big 3. Yes it is. I was on my 14th month of taking the antibiotics. I just returned from the Mayo Clinic where I had another CT and a bronchoscopy (I do not cough so have no sputum to test). The preliminary test came back positive for Mycobacterium. Now I need to wait 4-8 weeks to see which strain it is to decide which meds to try next. I felt great on the antibiotics with no symptoms at all so was pretty confident I was being healed. Now I am back to having the usual MAC symptoms of nausea, stiff muscles, hot, headache and a new one this time; tingly/burning hands and feet. Have any of you had luck with treating any of these symptoms with either OTC or prescribed medications? I've tried Aleve, Tylenol, Zantac and Zofran with no relief at all. I would be grateful for all recommendations you might have!