@lily2013 Hi Again, Lily. I have just done some study on your facial swelling, and I think I have found the name of the disorder. It is probablya Light Chain deposition, although some say it is a primary systemic amyloidosis. "Localized Cutaneous Amyloidosis. It can be monitored for several years without the need for therapy. Treatment may be recommended for patients with severe pruritus or for cosmetic reasons. The type of therapy will depend on the form of amyloidosis. Deposits of nodular primary cutaneous amyloidosis can be excised surgically or treated with carbon dioxide laser". There is a lot more on this on "Amyloidosis - Diagnosis and Treatment", ed. by Morey Gertz, Mayo-MN, with papers by Angela Dispenzieri and others. It is available through any bookstore. It is expensive, but there is much info in it. I won't bother quoting a lot more of it. Your doctor and you can contact Mayo-MN, Mass General, Sloan-Kettering, etc, for info, but my first step would be find out what Mayo Videos and writings have about this. It is a "Lichen Amyloidosis", while mine is "Macular". If you treat it in almost any way, it will re-occur. Antihistamines, corticosteroids, etretinate, and others have been used. DMSO 50% in water may have some benefit. Sometimes it progresses to systemic amyloidosis years later. In any case, you have a lot to learn about, now. old karl https://bit.Ly/1w7j4j8 Amyloidosis