Hi @charlie333, I had not heard about elevated liver enzymes or experienced them when my PMR was active but did find some information that mentions elevated numbers.

Liver Involvement in Polymyalgia Rheumatica: https://pubmed.ncbi.nlm.nih.gov/1006209/

Have you had tests that show you have elevated liver enzymes?

Hello Charlie. At one point I had elevated "everything" as I believe my body was reacting negatively towards this very complicated medical issue and the steroids. I was sent to a hematologist that was very good and I am so thankful for him as he ruled out everything else and diagnosed me with PMR - as all other doctors were stumped as to why I felt so sick, was so weak and in such pain. I have only one advise for EVERYONE. Get OFF the steroids, take the rapid release Tylenol, go see a really good chiropractor for the stiffness and pain in your neck and shoulders & include physical therapy and stretching. Your PCP will be happy to give you the RX for this therapy.
It took 4 months and today I can say that I have very few episodes of pain. Mostly a little stiffness and then I stretch my neck gently holding old the different stretches for 10-15 seconds. I do this throughout the day and believe me it works. I can now carry items like groceries, boxes, etc which I could not do before as my arms and hands were so weak I could not even open a shampoo bottle. I am not a quitter! PMR is terrible! I can see where it would be so easy to just keep on the steroids as they really do work. But it only masks the problem - they fix nothing. I take walks to strengthen my legs and lungs and feel so much better. Also, My mind is back to being clear. Not sure if you have any symptoms of GCA. I had immense tenderness on my scalp that moved to different areas daily and at one point could not even put my head back on the head rest in the car. Although the neurologist said he did not think I had GCA as I had no pain in my temples; it was odd that I had all the pain on my scalp. With my chiropractic care, the physical therapy and slow increase of activity/exercise that too is almost completely gone! I know this was long but I want people to understand that this can be made better without steroids, and that with time you can feel pretty much back to normal 🙂