Hi RBassett, I get my tincture from a local store, where they are great at working with people like me trying different formulations. I don't like hemp oil, for example, and started the tincture at 250 CBD and 150 THC which didn't make much difference. Have worked up to 1000 CBD and 50 THC, called "CHILL" and I take it at bedtime. It helps, but it's not magic...wish it were.