I take pyridoxal-5-phosphate which is very effective at preventing the damage from AGEs (Advanced Glycation End Products). I get 37.5 mg twice per day in Life Extension’s Two Per Day supplement. I take one with my early meal and one with the evening meal. I also take a 100 mg cap of pyridoxamine-5-phosphate in between these two meals. This is within the safety range. I take this along with carnosine, alpha-lipoic-acid, and Benfotiamine to prevent AGEs and I also eat a diet low in AGEs. Diabetes is accelerated aging as a result of the excess glycation of proteins and lipids so it’s best, in my opinion, to have a safe and effective approach to preventing the damage caused by diabetes. Here is a very simple article about eating a diet low in AGEs. http://www.diabetesforecast.org/2014/11-nov/foods-high-in-ages.html