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B-6 vitamin danger!

Neuropathy | Last Active: May 7 12:13pm | Replies (294)

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@jhkeffer

Here is an additional case which is highly likely an example of Vit B6 toxicity. My 73 y.o. wife developed severe burning on the soles of the feet which made sleep very difficult. When she shared it with me (M.D./Pathologist, retired), I hit the literature to explore possible causes that might be diagnosed by her general physician. As noted, this phenomenon is often idiopathic (no known cause) though myeloma protein, lupus, etc. and, oh yes, excess pyridoxine (B6) are known to be causes. Next step, to check my wife's vitamin bottles: multivites 2/day X 50 mg, plus B vitamins at "200 mg" day. Literature states anywhere from 100 and up may be toxic. Next step: discontinue both. watch and wait. One week later, after several nights of wonderful sleep, we conclude that this is highly likely to have been a case of pyridoxine toxicity (Thank the Good Lord!). So, beware out there. Joseph Keffer, M.D.

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Replies to "Here is an additional case which is highly likely an example of Vit B6 toxicity. My..."

Hello Joseph @jhkeffer, Welcome to Connect. Thank you for sharing how B6 toxicity affected your wife. It's great to hear that discontinuing the multivitamins made a difference. Most people don't understand the impact and just think it's only vitamins...vitamins are good for you. A person really has to be their own advocate and learn as much as they can about their health. It's awesome that your wife has her own live in doctor who can be her advocate. Thanks again for sharing on Connect.

There is another discussion on Connect that you may be interested in (just in case).

> Groups > Neuropathy > Burning Feet syndrome
-- https://connect.mayoclinic.org/discussion/burning-feet-syndrome/