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B-6 vitamin danger!

Neuropathy | Last Active: Dec 18, 2023 | Replies (278)

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@cokie63

I just joined today. I’m really confused why I have 106.7 B6 and 1303 B12 levels when I only took the supplements for 3 weeks at 16.7 mg of B6. I have horrible peripheral neuropathy head to toe. Mine started 4 days after my flu vaccine in November 2018. I have seen 3 foot doctors, a neurologist, neurosurgeon, 2 eye doctors because my eye balls burn too, ER 3 times for unexplained pain, cardiologist, MD and naturopath. I’ve had almost every test and extensive blood work. The neurologist told me my symptoms were from the supplement but I find that hard to believe because of the timing. My naturopath is checking my homocysteine and folate to see if I’m actually B deficient. The few things I’ve found that have helped me are compression socks/clothes; cayenne and crushed red pepper does something positive so I can feel instead of just burn(serotonin?) sleep also helps and lastly, I’ve been having night sweats for over a month and each time I do, the next day I feel like I’m getting a bit better. I’m waiting for a spinal tap. I’ve been home bound for 3 months and I walked my dog today. Each step felt like someone playing a wild electrical guitar inside my body. Gabapentin helps for sleep. Can’t believe the horrible sensations yet lack of feeling yet terrible muscle pain with this.

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Replies to "I just joined today. I’m really confused why I have 106.7 B6 and 1303 B12 levels..."

Hi @cokie63, welcome to Mayo Clinic Connect. I have no medical training or background but from all that I have read about vitamin B6 it's processed different by your body. High levels can be toxic and cause neuropathy. B12 is different. The body gets rid of what it doesn't need. You are good being your own advocate and learning as much as you can about your condition. I can believe it's from taking a supplement. Have you asked your neurologist/doctor how long it takes for the body to get rid of the excess B6?

Elevated B6 levels and peripheral neuropathies.
-- https://www.ncbi.nlm.nih.gov/pubmed/18754531