Thank you, John. I took Human Biology, Anatomy, and Nutrition but that was 10 years ago; new research may have yielded new results that I am unaware of. At that time, I learned that the B vitamins are water soluble, whatever our body doesn't use gets excreted in the urine harmlessly; B Vitamins do not build up in the body, as do oil soluble vitamins, A, D, E.