Hello @linnythepoo - I love that user name! Welcome to Mayo Connect - I'm happy you found us. It is a great place to ask questions, share your health concerns and learn what others with similar health issues are doing for treatment. Yikes is right from my perspective but I have no medical training or background. I would want to get an opinion or see a neurologist first.

Have you received a diagnosis of a form of neuropathy from a neurologist or had any tests to confirm the diagnosis?

I had a roundabout discussion through a 3rd party who I asked to check out a list of supplements that I'm taking for my peripheral neuropathy and this person giving the opinion was a neurologist. They said meh to my supplements and said they would probably recommend Metanx which contains L-methylfolate calcium, an active form of folate, and other essential B vitamins (B6 and B12) instead. B12 is in my list of supplements but I had already heard some bad stuff about B6 so I filed her opinion away under the category - it's my body, my decision. It's really a good idea to learn everything you can about your health condition and any drug used for treatment paying close attention to any side effects. I don't have any medical training or background so this is just based on my opinion and how I've dealt with my own idiopathic small fiber peripheral neuropathy.

Here's a more reliable source from the University of Virginia Health System - Peripheral Neuropathy and Vitamin B6 (PDF):
https://cancer.uvahealth.com/images-and-docs/neuropathy.pdf
Hope this helps,
John

I am also taking b6 as per my oncologist for neuropathy due to chemotherapy and I have noticed no change at all.

This is so crazy to hear about. Just last week my neurologist told me B6 causes neuropathy. So why are our oncologist feeding it to us like candy. It is crazy. Rb6 level should be 125 or less! I just had mine done they just do a blood test and mine was 292.8 no wonder my feet are falling off

I was told to take b100 for my nerve damage which was caused by the anastrozole . It has helped me but still have problems with my hands at least twice a week compared to everyday . I have been taking it for about a month

That is not a toxic dose.