Thank you, John, for the very informative link about Vitamin B6. I've been on a medically prescribed dose of 1000 mg of B6 and high doses of B12 and folic acid for about 35 years. I'm scheduled to see a neurologist at Washington University medical school in February, and hope that he'll test for the MTHFR gene and, I pray, figure out the cause and treatment for my small fiber polyneuropathy (Both feet and both legs all the up into my groin and in both hands.)

Hi @steeldove, can you talk with your doctor and request to be tested for the MTHFR gene? I'm not a doctor and have no medical experience but if your symptoms are getting worse it could help them figure out the cause of your symptoms. I would make a list of all the questions on your mind about your symptoms and your current treatment to find out if there are any new treatment options for you that would help. If you go in with your list of questions, it will be easier to communicate with the doctors and also help them.

If you don't mind and are able to share the outcome of your appointment in February, I think it would be really helpful for other members on Connect.

Wishing you and all our Connect members a Happy pain free Holiday season.

John

Hi John I'm new to this recently diagnosed with prepheral neuropathy, don't know how to start a discussion on here.

Hello. My latest two vitamin B6 lab results (24 hours without my supplement) showed my B6 is abnormally high; double what it should be! I didn't realize I've been taking 50mg. in my Max Potency Multivitamin/Mineral supplement. I need to find an equivalent WITHOUT so much B6 in it. Does anyone have any suggestions? I have a lot of disease in my body besides Neuropathy so need a very good all-around multi-vitamin/mineral supplement b/c I don't eat very much. Thank you so much! Sunnyflower

Thank you, that is a wonderful site