← Return to Stage 4 inoperative squamous NSCLC, now on Opdivo last line Tx

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@burrkay

So sorry to hear about your NSCLC!
I am a caregiver for my wife, who was diagnosed with Adenocarcinoma, stage 3a NSCLC in May, 2015. Her cancer had not metastasized at that time so Mayo removed 2 lower lobes of her right lung. After going thru chemo therapy, her scan the following year showed the tumors had grown and our Mayo oncologist re-staged her to stage 4 inoperable NSCLC.
He put her on Opdivo, but after 4 months of the therapy, the scans showed that she was not responding. The Mayo oncologist then ordered a lung biopsy, which was sent to Foundation One in Boston for a molecular study.
The study showed her mutation, although in her lungs was indeed a HER2 mutation, normally found in breast cancer patients. Our Mayo oncologist then put her on infusions of a trial doublet of herceptin and PERJETA.
My wife is still responding well to the infusions every 3 weeks. The last PET CT scan showed the tumors have stablized, for which we are extremely grateful. We are convinced that the Mayo oncologist who ordered the Trial is our guardian angel!
Although yours is a squamous cell (different that Adenocarcinoma), I would suggest you to talk with you oncologist about the possibility of having a molecular study done...best of luck...God bless!

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Replies to "So sorry to hear about your NSCLC! I am a caregiver for my wife, who was..."

Thank you for your reply. I appreciate your time. I initially had three biopsy's so we know what they are dealing with. If they could have cut it out, things would look differently today. But it was to close to my heart, and now the new mutations are entangling one of my airways in the other lung. We will ask about other treatment options if the Opdivo isn't working. Will have a CT scan in January if all is well. So we will just hope and pray for good results in January .We just take it one day at a time, and enjoy our family and each other. Each day is a gift and we are thankful for what we are given. Blessings to you and your wife, and wishes for a wonderful Christmas Season.