Hi @fox940, I suffered for a year from drug-induced lupus. My pharmacist was the one who figured it out because he took the time to read the full-length medication documentation from the manufacturer. What was interesting was that the words "autoimmune" and "drug induced lupus" weren't even in the documentation. It only said a brief paragraph stating that some patients develop "antibodies" to the medication.

Thanks for the information. I read it and unfortunately besides the comments about Drug Induced Lupus don't seem to fit me very well.

What's crazy is I look like I should be the picture of health. My tests are outstanding besides the positive Anti-Histone AB. My inflammatory markers are normal and all other blood work is normal. I don't have the skin conditions some with regular lupus have. I also don't suffer from chronic fatigue like some. I had a blood metal allergy test done in August after having the metal clips surgically removed and the tests were negative so it may not have been the metal clips causing my issues though my joint pain and muscle weakness improved. I just suffer from the severe muscle/bone pain now. I do have what I call "lupus attacks" where a day or two every 4 weeks or so I do suffer from fatigue and worse pain than usual. When this got real bad around June 1 that is what I thought was happening, but besides the fatigue it hasn't went away like it would before I had surgery. When I am having a "flare" where the pain is worse than normal I get fatigued, but I'm pretty sure it is just being wore out from the chronic pain. I'm 6'3" and 185 pounds and am in good shape. Looking at me from the outside I look like a very healthy person and in great shape for my age. I have to eat a strict diet due to my food allergies so I have to eat healthy. I pretty much follow the Auto-immune Paleo diet. I keep my sugar consumption very low as well as avoid processed foods, etc. I've read that Autoimmune Disease is an Invisible Illness and that makes a lot of sense. I am close to Denver and the medical community in this region of the US doesn't seem to know what is wrong with me. I go to a Dr. that is within a large network of hospitals up and down the front range of Colorado. I've been going to a PT that specializes in Pelvic Floor Physical Therapy and that has helped that region of the pain, but when I flare it seems like any gain is reversed back to where I suffer from the pain. Hopefully the physicians at the Mayo Clinic can give me an answer though I'm starting think I'm an anomaly.