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Can anybody share about being on SEROQUEL?

Depression & Anxiety | Last Active: May 25, 2022 | Replies (91)

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@leonarda

My spouse was prescribed 25mg Seroquel after suffering a depressive episode and paranoia triggered by some health issues that required after care following knee surgery because of a staph infection. Primary doctor felt it could be PTSD and psychiatrist is confident in decision to prescribe this drug. Spouse is very fearful of medications so having a hard time starting and staying on. Tried full dose, was scared off by sedation and tried 1/2 dose and couldn’t sleep. Next attempt at 1/2 was a day later and resulted again in no sleep and actual burst of energy at midnight. Doc says it’s okay to go back to full dose but again, my spouse would not. I’ve seen glimpses that even that small amount helped and hope that we can continue. Has anyone ever tried every other day taking 25 mg with good results?

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Replies to "My spouse was prescribed 25mg Seroquel after suffering a depressive episode and paranoia triggered by some..."

@leonarda I used Seroquel until it didn't work anymore (didn't want to increase dose). A 25mg tablet is the lowest that Seroquel comes. I used that dose every night, never tried every other night. Can't see why it wouldn't work though.

@leonarda, welcome to Mayo Clinic Connect. You'll notice I moved your post here to a larger discussion of your topic on quetiapine (Seroquel). If you click on VIEW & REPLY in your email notification, you will see the whole discussion and can join in, meet, and participate with other members talking about their or their loved ones' experiences.

Glad you got to meet @falon and got some input on this medication. Sounds like you think this drug has promise for your spouse, but the full dose led to too much sedation and 1/2 dose led to lack of sleep.

This Mayo Clinic information on this medication and how to use it may be helpful https://www.mayoclinic.org/drugs-supplements/quetiapine-oral-route/description/drg-20066912.

I note one line in particular that may be relevant to your spouse, which is, "The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label."

Wondering if you or your spouse has talked to the prescribing doctor about the sleepiness/lack of sleep and whether he or she might have some thoughts on whether this is likely to continue, or whether there should be a change in the dosing?